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Table 1 Targeted therapies approved or in clinical trials

From: Proteomic analysis identifies highly expressed plasma membrane proteins for detection and therapeutic targeting of specific breast cancer subtypes

Therapeutics and their targets
Therapeutic Gene target MCF-7 SKBR3 DT22 DT28 MB-231 MCF-10A
Herceptin ERBB2 0 276 45 3 3 0
Gefitinib, Tarceva, Poziotinib EGFR 0 22 11 27 88 10
MM-111, Seribantumab, U3-1402 ERBB3 3 6 52 3 0 0
Bemcentinib AXL 0 0 0 0 58 0
  1. The therapeutic, gene target, and number of SCs identified in each cell line for that target are listed. MB-231 indicates MDA-MB-231 cells