Proteomic analysis identifies highly expressed plasma membrane proteins for detection and therapeutic targeting of specific breast cancer subtypes

Table 1 Targeted therapies approved or in clinical trials

Therapeutics and their targets
Therapeutic	Gene target	MCF-7	SKBR3	DT22	DT28	MB-231	MCF-10A
Herceptin	ERBB2	0	276	45	3	3	0
Gefitinib, Tarceva, Poziotinib	EGFR	0	22	11	27	88	10
MM-111, Seribantumab, U3-1402	ERBB3	3	6	52	3	0	0
Bemcentinib	AXL	0	0	0	0	58	0

The therapeutic, gene target, and number of SCs identified in each cell line for that target are listed. MB-231 indicates MDA-MB-231 cells

ISSN: 1559-0275